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... %. Accurate determination of the sequence is, therefore, critical for variations in DNA sequence can have a major impact on how humans respond to disease, bacteria, viruses, drugs and therapies. The current sequencing technologies, although a big improvement over the techniques used at the start of the HGP, needs a 2 or 3-fold improvement to achieve the required goals. It is one of the challenges facing the scientists at the Project and a lot of effort is being put into the sequencing technology research.
Informatics is the creation, development, and operation of databases and other computing tools to collect, organize, and interpret data. It is a new field of research developed to handle the computing challenges peculiar to the HGP. Expanded databases and special analytical software tools for studying and making sense of the enormous amount of complex sequencing data are being developed.
The Size of a Genome
Although the physical size of genome is extremely small, the amount of data contained by them is mind-boggling. For example, 200 volumes of 1000 page books would be required to hold the DNA sequence of the human genome and it would take about 9.5 years to read out the 3 billion bases in a personís genome sequence.
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